One of the seven Offspring of Callisto and Sinope, Lysithea followed her brother Anake into exile after he murdered their mother, bearing him two children: Rukal and Lakspura.
After Anake's death, Lysithea sought a means to return her brother to life. Taking advantage of the grief-stricken girl, Lorielan promised to help her, but instead tricked her into relinquishing her two pieces of the Sceptre of Divinity, and left her stranded upon the Crystal Plane.